Why the liquid medical silicone has high biocompatibility

Liquid medical silicone has high biocompatibility, which is specifically reflected in the following aspects:
Tissue compatibility:
Cell adsorption: Liquid medical silicone surface has weak adsorption capacity for cells, which will not cause excessive adhesion or aggregation of cells, thereby reducing the impact on the normal physiological function of cells. Cells can grow, migrate and differentiate normally on its surface, which is very important for some medical applications that need to contact with tissues, such as soft tissue repair and wound dressings.
No inhibition of cell growth: The material will not release substances that have an inhibitory effect on cell growth, and can provide a relatively suitable environment for cell proliferation and differentiation. For example, in some tissue engineering applications, liquid medical silicone can be used as a scaffold material to support cell growth and tissue regeneration.
Anti-inflammatory: The inflammatory response caused by liquid medical silicone is very mild. When implanted into the human body, it will not cause obvious inflammatory reactions such as immune cell aggregation and inflammatory factor release, reducing the risk of complications such as postoperative infection, redness, swelling, and pain.
Non-antigenic, non-mutagenic, non-carcinogenic, and non-teratogenic: Its chemical structure is relatively stable and will not be recognized as a foreign antigen by the human immune system, thereby avoiding the occurrence of immune rejection. At the same time, it will not cause problems such as gene mutation, cell canceration or fetal development abnormalities, and has high safety.
Blood compatibility:
Anticoagulant properties: Liquid medical silicone has good anticoagulant properties, which can reduce the coagulation and thrombosis of blood when it comes into contact with the material. This is crucial for some medical devices that are in direct contact with blood, such as vascular stents, heart valves, hemodialysis catheters, etc., which can ensure the normal flow of blood and reduce the risk of blood vessel blockage.
Antiplatelet thrombosis: The adhesion and aggregation of platelets on the surface of the material is one of the important steps in thrombosis. Liquid medical silicone can inhibit the adhesion and activation of platelets on its surface, thereby reducing the formation of platelet thrombi and improving the safety and effectiveness of medical equipment.
Anti-hemolysis: The material will not cause the rupture and dissolution of red blood cells, avoiding the occurrence of hemolytic reactions. This is very important for medical supplies that come into contact with blood, such as blood storage containers and blood transfusion catheters, which can ensure the quality and safety of blood.
Anti-complement system hyperactivity and anti-cytokine adsorption: Liquid medical silicone will not over-activate the complement system, avoiding the immune damage caused by over-activation of the complement system to the human body. At the same time, it will not adsorb too many cytokines, thereby reducing the impact on cell signal transduction and immune regulation.